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LIFE SCIENCE
New framework enhances genetic prediction of drug response and side effects
A UCLA study has outlined a new framework that researchers say would improve predictive power of genetics to determine how well a patient would respond to commonly prescribed medications as well as the severity of any side…
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PAGER technology unlocks new potential for controlling cellular activity
A basic function of cells is that they act in response to their environments. It makes sense, then, that a goal of scientists is to control that process, making cells respond how they want to what they want.
One avenue for…
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Study uncovers dangerous side effects of AZD7648 in gene editing
Genome editing with various CRISPR-Cas molecule complexes has progressed rapidly in recent years. Hundreds of labs around the world are now working to put these tools to clinical use and are continuously advancing them.…
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Study reveals how stem cells sense and respond to their environment
A new study from The Hospital for Sick Children (SickKids) and Institut Curie reveals how stem cells sense and respond to their environment, with implications for inflammatory bowel disease and colorectal cancer.
Stem cells …
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Spatial transcriptomics uncovers new treatment paths for triple-negative breast cancer
Researchers reveal the intricate molecular landscape of triple-negative breast cancer (TNBC), uncovering actionable spatial archetypes and gene signatures that pave the way for personalized therapies and better outcomes.…
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Minority genetic variation in tuberculosis offers new insights for improving outbreak tracking
Study highlights the potential of minority variation and alternative sequencing methods to enhance epidemiological understanding of TB transmission
Study: Signatures of transmission in within-host Mycobacterium tuberculosis…
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Alzheimer’s genetic risk studies undermined by systemic biases
New research reveals that biases in genetic studies on Alzheimer’s may distort risk predictions and derail medical advancements, but a novel approach offers hope for uncovering the truth.
Study: Pervasive biases in proxy…
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Immune cells play a key role in movement control and metabolic balance
Immune cells have a surprising and critical role in controlling movement and bridging neural activity with metabolic demands, concludes a groundbreaking study published in Nature by researchers at the University of Copenhagen…
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Cancer cells block T-cell activation, but new therapies restore immune defenses
New findings reveal how cancer manipulates immune pathways and highlight therapeutic strategies to unleash T-cells against even the most resistant tumors.
Study: Cancer cells impair monocyte-mediated T-cell stimulation to…
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Aging reduces cancer risk by limiting cell regeneration
When it comes to cancer, aging is a double-edged sword, researchers are increasingly learning.
Age is considered the most important risk factor for cancer. That's because genetic mutations build up in cells over years and…
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