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LIFE SCIENCE
Multi-omic profiling sheds light on chemo-immunotherapy resistance in lung cancer
Researchers use spatial transcriptomics to uncover tumor microenvironment patterns linked to treatment response in non-small-cell lung cancer
Study: Multi-omic profiling highlights factors associated with resistance to…
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New protein platform enhances cancer immunotherapy
Researchers from Children's Hospital of Philadelphia (CHOP) and Stanford University have revealed the molecular structure of TRACeR-I, a protein platform for reprogramming immune responses. A better understanding of its…
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Disrupting the circadian rhythm of glioblastoma slows tumor growth, study says
Virtually every cell in the human body has an internal clock. These clocks take their cues from a central clock in the brain. In a normal, biological process called synchrony, the central clock coordinates daily rhythms around…
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A genetic variant modulates interferon signaling and disease risk
Why does the COVID-19 virus make some people sicker than others?
For years, scientists have looked to a critical piece of immune system machinery - known as the interferon pathway - for answers. There, when our cells sense an…
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Fatty acids disrupt glutamate transporter function in brain cells
Glutamate transporters pump glutamate from the synaptic cleft back into brain cells after its release during neurotransmission. A new study by Weill Cornell Medicine investigators has found that free fatty acids, including an…
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Virus causes 20 million infections annually as study uncovers hidden drivers of its evolution
Researchers examine the evolution of hepatitis E virus, which infects 20 million people annually and causes 44,000 deaths worldwide
Study: Ancient evolutionary origins of hepatitis E virus in rodents. Image Credit:…
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New study uncovers role of amino acid serine in preventing food poisoning
Food poisoning is a common, yet unpleasant, illness caused by eating contaminated items. It is sometimes caused by Clostridium perfringens, a pathogen widely found in soil and the intestinal tracts of animals.
The pathogen…
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Addressing inequities in cardiovascular drug access
A new study assessing provincial and territorial variations in reimbursement criteria of drug coverage for patients covered by Canada's public pharmacare programs for two common cardiovascular conditions revealed significant…
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New tool accelerates drug discovery
New tool accelerates drug discovery
Source link : News-Medica
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Harnessing exosomes to deliver therapeutic proteins
Researchers at The Ottawa Hospital and the University of Ottawa have discovered an 18-digit code that allows proteins to attach themselves to exosomes - tiny pinched-off pieces of cells that travel around the body and deliver…
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